Motorcycles subject tyres to an enormous range of forces, stresses and heat. More so with modern dual purpose bikes.
Most motorcycle tyre failures are as a result of low tyre pressures and excessive weight. This is why tyre manufacturers rate tyre pressure as the number-one priority and strongly urge riders to check it regularly. So, if one is going to become fanatical about anything, it should be about religiously checking your tyres and avoid the sins of overloading them.
Overload and under inflation creates flex in the tyre and an excessive heat build-up that can negatively affect handling and could ultimately result in tyre failure for any kind of tyre.
To counteract this, Heidenau specifically design their tyres with an extremely strong side wall.